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It is important to identify non-valvular atrial fibrillation NVAF patients at risk of thromboembolism, and to appropriately administer antithrombotic therapy to them. On the other hand, it is also important to identify truly low-risk patients because bleeding complications related to antithrombotic therapy are not uncommon. The CHA 2 DS 2 -VASc score has been proposed as a method of evaluating the risk levels of such patients, and this score includes vascular disease, age of 65—74 years, and female sex as risk items. Although a CHA 2 DS 2 -VASc score of 0 indicates an extremely low risk for thromboembolism, a woman would be allocated 1 point in this scoring system from the time that she was born. It is therefore apparent that the CHA 2 DS 2 -VASc scoring system has limited applications if it does not clarify at what age the risk of thromboembolism begins to increase in women. Circ J May 13, doi

There were significant c-statistic difference 0. Circ J ; — Numerous studies have shown that female sex is a risk for thromboembolism in Caucasian patients with nonvalvular atrial fibrillation NVAF. A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: The Framingham Heart Study.

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