Sex pci

What is the association of sex with patient outcomes at 2 years after contemporary percutaneous coronary intervention PCI and with the efficacy and safety of two antiplatelet strategies? The main study enrolled 15, unselected patients undergoing PCI between July and November Patients had an outpatient clinic visit at 30 days and 3, 6, 12, 18, and 24 months after the index procedure. Eligible patients were randomized to either the experimental or reference antiplatelet strategy. The experimental strategy consisted of 1 month of dual antiplatelet therapy DAPT followed by 23 months of ticagrelor monotherapy, while the reference strategy was comprised of 12 months of DAPT followed by 12 months of aspirin monotherapy. The primary efficacy endpoint was the composite of all-cause mortality and new Q-wave myocardial infarction at 2 years.
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Death, Cardiac Events More Frequent in Women than Men Following PCI

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Association of Sex With Outcomes in PCI Patients - American College of Cardiology

Published online in JAMA Cardiology , the study also found that the risks of bleeding and haemorrhagic stroke were higher in women than men, and that ticagrelor monotherapy was associated with a lower risk of bleeding than dual antiplatelet therapy at one year in men, but not in women. GLOBAL LEADERS was an investigator-initiated, prospective, randomised, multicentre, multicontinental, open-label trial to evaluate two antiplatelet therapy strategies after PCI using uniformly bivalirudin and biolimus A9—eluting stents Biomatrix in an all-comers population with no restrictions on clinical presentation, complexity of lesions, or number of stents used. The current analysis, by Ply Chichareon Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands, and Prince of Songkla University, Songkhla, Thailand et al, aimed to assess the association of sex with patient outcomes, and with the efficacy and safety of two antiplatelet strategies. The main study enrolled 15, unselected patients undergoing PCI between July and November
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Association of Sex With Outcomes in PCI Patients

The data are overwhelming and not uncommonly, the results are often discrepant. So, what do we know about CAD in women? We know that there are clear differences by sex in the presentation of patients with CAD. Yet, many of the differences in outcomes have been attributed to sex differences in the presentation and treatment of these patients.
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Women are more likely to suffer from a cardiogenic shock CS as the most severe complication of an acute myocardial infarction AMI and tend to have a higher mortality. Data concerning optimal management among women with CS are lacking. Aim of this study was therefore to better define characteristics of women suffering a CS and to investigate the influence of sex on different coronary revascularisation strategies. Primary end-point was a composite of death from any cause or severe renal failure leading to renal-replacement within 30 days after randomisation.
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